Tomatillos are low in calories. 100 g of berries provide just 32 calories. For comparison, they carry a bit more calories, fat, and protein than tomatoes. (100 g tomato just has 18 calories). Besides, they contain many health benefiting plant nutrients such as dietary fiber, minerals, antioxidants, and vitamins. Unlike tomato, tomatillo does not carry lycopene. On the other hand, it is good in different kind of antioxidant phytochemicals known as withanolide.s Ixocarpalactone-A is one such withanolides present in tomatillo which has been found to have antibacterial and anti-cancer properties. Tomatillo contains small amounts of antioxidant vitamins like vitamin-A, vitamin-C, and vitamin-E. Further; the berry consists of flavonoid antioxidants such as ß-carotene, zeaxanthin, and lutein. These compounds possess antioxidant properties and, together with vitamin-A, are essential for ocular health. Besides, Vitamin-A is also required for maintaining the integrity of mucosa and skin. Consumption of natural vegetables and fruits rich in flavonoids help protect from lung and oral cavity cancers. Fresh tomate is one of the vegetables that has the least sodium to potassium ratio (0:6). Potassium is an important component of cell and body fluids that help regulate heart rate and blood pressure. Further, the fruit has more minerals weight per weight basis than that in the tomatoes. They are also a good source of copper, iron, phosphorous, manganese, and other minerals.